What is HHCPM, how is it produced and what are its effects?
- What is HHCPM or hexahydrocannabiphorol monomethyl ether?
- HHCPM production
- Structure of the HHCPM
- How HHCPM works
- HHCPM products: safety, legality and product offering
- Conclusion
What is HHCPM or hexahydrocannabiphorol monomethyl ether?
HHCPM stands for hexahydrocannabiphorol monomethyl ether. Hexahydrocannabiphorol, which stands for HHCP, is hidden in the name, and the term monomethyl ether refers to a specific type of ether group.
The cannabinoid HHCP (hexahydrocannabiphorol) is a derivative of HHC (hexahydrocannabinol), which is found in the cannabis plant but is now more commonly produced from more readily available precursors such as CBD (cannabidiol) or terpenes. HHCP differs from HHC in that it has two carbons longer alkyl chain.
HHCPM is reported to be ethylated, hydrogenated phorbol THC. HHCPM can be described as a derivative of HHCP, whereby the addition of an ethyl group changes the original structure of HHCP.
This compound is produced exclusively in the laboratory and is a (semi)synthetic cannabinoid.
HHCPM production
HHCPM is the result of complex chemical processes that typically involve several key steps, including the synthesis, modification and purification of the base cannabinoids.
HHCPM goes through several processes, such as:
- Hydrogenation: a chemical reaction in which hydrogen molecules are added to the molecular structure of a cannabinoid. This increases the stability and lipophilicity of the molecule, which can influence what effects it will have on the body.
- Adding an ethyl group (CH2CH3) to a part of the molecule
- Methylation of the oxygen group -CH3 into the molecule, resulting in a methyl ether, which can affect the solubility and potentially the biological activity of the substance (interaction with body receptors)
The resulting HHCPM product has a low viscosity, which means that it is relatively liquid.
Structure of the HHCPM
The molecular formula of HHCPM is C24H38O2 (C24 - 24 carbon atoms, H38 - 38 hydrogen atoms, O2 - 2 oxygen atoms).
And since it is a hydrogenated compound, like HHC and H4CBD, it consists of two different stereoisomers, namely molecules:
- 9(R)-HHCP methyl ether
- 9(S)-HHCP methyl ether
Scientists have already discovered that the (9R) isomer binds very effectively to CB1 receptors in the endocannabinoid system (ECS), causing a psychoactive effect, whereas the 9(S) molecule carries the inactive element label.
In 2023, a study focusing on the cannabinoid HHC found that the 9(R) isomer binds with high affinity to CB1 and CB2 receptors and has almost the same activity as THC. In contrast, isomer 9(S) showed low activity in functional assays.
How HHCPM works
As it is a completely new cannabinoid, there are no studies yet on how it works in the body and what effects it produces.
Like other psychoactive cannabinoids such as HHC, HHCP, THCP and THCJD, it can be expected to induce changes in perception, feelings of euphoria, relaxation and increased appetite.
The effects of HHCPM will depend not only on several factors such as the age, body proportions, experience, sensitivity and metabolism of the user, but also on the route of administration and the efficacy of the product.
With vaporisation, the effects can take between 25-60 minutes, the peak effects can last 1-3 hours, the total duration of action can be 3-6 hours and the decline in effects can be between 2-3 hours.
In the case of edibles, the onset of effects can take 60-90 minutes, peak effects can be felt 2-4 hours, overall effects can last 6-12 hours, and the decline can last 6-10 hours.
Effects of HHCPM: What do the experiences and reviews from the Internet say?
The e-commerce site cannabinoidswithturkey.com lists a user's opinion on HHCPM:
HHCPM is unique because it acts as the most potent cannabinoid that maintains the feeling of "spaciness".
In terms of potency, the user stated that it is similar to HHCP.
Regarding the duration of effects, he reported that HHCPM acts slightly faster than HHCP, but the peak is not as long. However, the "comedown" (decrease in effects) appears to be significantly longer. The peak effects do not last as long, but the overall effect could be even longer than for HHCP.
On the Reddit discussion forum, users have also been discussing their experiences with HHCPM. One of them, for example, said that the pre-roll (pre-rolled joint) was quite strong and that he felt the effects for longer than he expected, but that the peak effects were not as pronounced and that he felt brain fog by the second day.
Another user wrote that he tried 30% HHCPM in a vaping cartridge and felt no significant effects, it reminded him of the intensity of the effects of H4CBD.
Side effects
HHCPM is psychoactive and can therefore affect perception and cause side effects (especially if too high a dose is taken), including:
The listing of these potential adverse effects is based on analogue derivatives or cannabinoids that have psychoactive properties. The side effects of HHCPM have not yet been investigated, so it is currently unknown how it affects the body in the long term.
HHCPM products: safety, legality and product offering
At the moment, there are no studies to evaluate whether the use of HHCPM is completely risk-free. In addition, each substance inherently carries a potential risk of adverse effects.
At the moment, new cannabinoids are not even regulated and are generally in a 'legal grey area', so there is some concern that products will appear on the market contaminated with heavy metals or other unwanted and potentially dangerous substances.
When sourcing cannabis products, always make sure to buy from reputable companies and prefer brands that offer transparency and results from third-party labs.
In terms of legality, HHCPM is currently an approved substance in most European countries. It is banned in Bulgaria and Austria, for example. Users should always check local legislation and respect the laws of the country in question.
HHCPM product range
The most common HHCPM products on the market are:
Conclusion
HHCPM (hexahydrocannabiphorol monomethyl ether) is a psychoactive cannabinoid that is produced in laboratories. The name includes hexahydrocannabiphorol (HHCP) and monomethyl ether (a designation for a specific type of ether group).
It should be added that (semi)synthetic compounds can be much stronger than natural ones, which multiplies the possible risk of intoxication and overdose, which can end up in a so-called "bad trip".
In the current absence of research, the reality is that until HHCPM and other cannabis derivatives are regulated, it remains entirely up to consumers to evaluate the potential risks and benefits of these compounds for themselves.
If you are tempted by new compounds, always buy from trusted companies and check the product ingredients to ensure there are no unsuitable additives or fillers.
Approach similar substances with discretion and respect.
Author: Canatura
Photo: ChatGPT
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