What is CB9? Origin, effects, availability and comparison with other cannabinoids
- What is CB9?
- Origin and chemical composition of CB9
- Properties of CB9
- Psychoactive effects of CB9
- Therapeutic potential
- Interaction of CB9 with the body's endocannabinoid system
- Table comparing CB9 with the cannabinoids CBD, H4CBD, HHC and THC
- Availability
- Conclusion
What is CB9?
CB9 is a derivative of CBD (cannabidiol). Found in the cannabis plant, it is one of more than 100 identified cannabinoids in the plant. It has a natural 5-carbon tail and a chemical structure similar to the more familiar CBD. But as we know, even a slight change in chemical structure will cause the effects of cannabinoids to be different. This is also the case for the compound CB9, which, unlike CBD, is psychoactive.
The detection of CB9 is much more complicated than for other cannabinoids, which poses a major challenge for scientific research.
The origin and chemical composition of CB9
Properties of CB9
CB9 has a similar structure to the cannabinoids CBD and H4CBD, but stands out for its psychoactive properties. However, its unique properties require extensive scientific analysis, improved detection methods and careful consideration of the regulation of this substance.
Conventional analytical procedures using HPLC (high performance liquid chromatography) may not be sufficient to recognise CB9. It is this obstacle that points to the need for improved testing methods in the analysis of cannabinoids.
Psychoactive effects of CB9
Therapeutic potential
The therapeutic uses of CB9 are remarkable and, although research into this cannabinoid is still in its infancy, its future looks very promising. Research is currently underway to see if this compound could be beneficial in the treatment of various medical conditions such as chronic pain, inflammation and possibly neurodegenerative diseases.
Interaction of CB9 with the body's endocannabinoid system
Cannabidiol is known for its molecular structure, which does not cause psychoactive effects. Although CB9 is a derivative of CBD, it has a specifically modified chemical structure that causes the psychoactive properties already mentioned. Understanding why and how these structural changes affect interactions with receptors in the endocannabinoid system (ECS) is an important milestone for new discoveries in both the medical and therapeutic spheres.
Most of the effects of cannabinoids are related to their ability to interact with our ECS. This system is responsible for various bodily functions such as mood, sleep, immunity, movement and appetite. There are 2 main types of endocannabinoid receptors, CB1 and CB2. CB1 receptors are mainly found in the brain and nervous system, while CB2 receptors are found in the immune system, digestive tract and other organs.
Although CBD has a low binding to CB1 and CB2 receptors and therefore has no psychoactive properties, it does act as a modulator of these receptors. In addition, it can affect other receptors in the body, including serotonin, adenosine and vanilloid receptors.
How CB9 interacts with the ECS is not yet known.
Table comparing CB9 with the cannabinoids CBD, H4CBD, HHC and THC
|
CB9 |
CBD |
H4CBD |
HHC |
THC |
|
|
Chemical formula |
C17H20N2O6S |
C21H30O2 |
C21H34O2 |
C21H32O2 |
C21H30O2 |
|
Occurrence in cannabis |
Yes |
Yes, the second most abundant cannabinoid |
No |
Yes, only in minute quantities |
Yes |
|
Production |
CBD derivative, produced by a complex chemical reaction in cannabis, with other cannabinoids such as THC and CBD serving as precursors. |
It is obtained by one of the extraction methods:
|
CBD derivative, produced by hydrogenation, by adding 4 hydrogen atoms to the CBD molecule. |
It is usually produced by hydrogenation from CBD or from terpenes (citronellal or olivetol). |
THC is formed in cannabis by converting its precursor, THCA, under the action of heat. |
|
Psychoactive properties |
YES |
NO |
MAYBE |
YES |
YES |
|
Effects |
Milder effects than THC. |
Not psychoactive. |
The H4CBD compound is similar to CBD in its effects, but with the difference that it binds more effectively to CB1 receptors. |
The effects are very similar to those of THC:
|
Strong and sometimes debilitating effects:
|
|
Interaction with receptors in the (ECS) |
Potentially different interaction with the ECS of the human body, resulting in unique effects. The interaction of CB9 with the ECS is still a subject of research. |
Low affinity, functions as a modulator of CB1 and CB2 receptors. It also affects adenosine, serotonin and vanilloid receptors. |
Molecule 9R H4CBD: likely high affinity for CB1 receptors. |
Molecule 9R HHC: probably high affinity for CB1 receptor (but lower than THC) and low binding to CB2 receptor. |
THC stimulates both CB1 and CB2 endocannabinoid receptors. |
|
Therapeutic potential |
Potential therapeutic benefits in areas such as:
|
Potential to:
|
Similar to CBD, but with a more pronounced potency. May contribute:
|
|
Especially in:
|
Availability
The cannabis market for CB9-containing products is likely to develop alongside scientific research. Currently CB9 distillate, flower, hash and CB9 vapes can be found in some e-shops. It can be assumed that as more is learned about this compound, innovative products may emerge that will be tailored to the specific properties and benefits of CB9. Not only will the cannabinoid market grow, but new opportunities will open up for both consumers and cannabis companies.
Given the constant changes in cannabinoid legislation, CB9 could represent a suitable alternative where other cannabinoids are restricted or banned.
Conclusion
The latest addition to the cannabinoid family, CB9 is a CBD derivative. Scientists are trying to get to the bottom of the molecular pathways by which it acts and affects the human body. Its potential to reduce stress and increase overall mental well-being could make it a promising substance in natural health care.
However, clinical trials are needed to evaluate its efficacy, safety and use. These studies will provide us with reliable scientific data on CB9 and its potential.
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